Database search
November 2009 release, R14

This tool is designed to search and download specific data and to analyze datasets contents.

If you have any difficulties in using this tool, or have any questions or comments regarding the web site, you may either contact us at , or read the help file that provides information on how to search and retrieve data, and on database annotations and contents, or check the FAQ.

Click on the images to go to search options. Search options and graphics have been optimized for PC computers using Internet Explorer 5 or later versions. Using other web browsers may not work properly. With Mac OS X computers, use Safari.


Search database for data related to SOMATIC MUTATIONS:

 Select: tumor type
 Retrieve: mutation pattern


Display the proportion of mutations grouped by type of base change, effect, codon position or functional impact in a selected type of tumor(s). (?)

Mutation pattern Function pattern
 Select: multiple criteria
 Retrieve: mutation pattern


Select more than 20 criteria to retrieve the mutation spectrum of a specific dataset. (?)

Advanced search
  
 Select: multiple criteria
 Retrieve: mutation prevalence


Search for TP53 mutation prevalence in selected types of tumor and populations. (?)

Mutation prevalence



Search database for data related to SOMATIC OR GERMLINE MUTATIONS:

 Select: mutation
 Retrieve: tumor spectrum


Display a histogram showing the distribution of tumors associated with the selected germline or somatic mutation(s). (?)

Tumor spectrum
 Select: mutation
 Retrieve: mutation summary


Check if the selected mutation exist and display a summary of data available for this mutation. (?)

Mutation analysis
 Select: multiple criteria
 Retrieve: cell-lines


Search the TP53 gene status of human cancer cell-lines. (?)


Advanced search

Search OTHER datasets:

 Select: mutation
 Retrieve: biological activities


Display biological activities tested in experimental assays in human or yeast cells. (?)
Mutant function
 Select: multiple criteria
 Retrieve: structures


Use various tools to retrieve data on structure of mutant p53 proteins (?)

3D analysis
  Search all datasets with SRS


SRS allow for multiple user-defined queries and data retrieval in table or html formats. SRS integration provided by Paolo Romano, IST, Genova, Italy.




  IST logo



  Polymorphisms

Display polymorphic sites with links to specialized databases (?)



Polymorphism

  Mouse models

Display mouse models with engineered TP53 (?)
  mouse
  Protein interactions

Visit Human Protein Reference Database to view p53 protein-protein interactions and post-translational modifications on p53.

HPRD logo



The search application has been created by Lambda-plus and further developed at IARC.