This tool is designed to search and download specific data and to analyze datasets contents.
If you have any difficulties in using this tool, or have any questions or comments regarding the web site, you may either
contact us at ,
or read the help file that provides information on how to search and retrieve data,
and on database annotations and contents. You may also check the FAQ.
Search options and graphics have been optimized for PC computers using Internet Explorer 5 or
later versions. Using other web browsers may not work properly.
Search database for data related to SOMATIC MUTATIONS
Select: tumor type or multiple criteria
Retrieve: mutation pattern
Display the proportion of mutations grouped by type of
base change, effect, codon position or
functional impact in a selected type of tumor(s)
(?) or by selecting
more than 20 criteria (?).
Select: multiple criteria
Retrieve: mutation prevalence
Search for
TP53 mutation prevalence in selected types of tumor and populations.
(?)
Search database for data related to SOMATIC OR GERMLINE MUTATIONS
Select: mutation
Retrieve: tumor spectrum
Display a histogram showing
the distribution of tumors associated with the selected germline or somatic mutation(s).
(?)
Select: mutation
Retrieve: mutation summary
Check if the selected mutation exists and display a
summary of data available for this mutation.
(?)
Select: multiple criteria
Retrieve: cell-lines
Search the
TP53 gene status of human cancer cell-lines.
(?)
Search OTHER datasets
Select: mutation
Retrieve: biological activities
Display
biological activities tested in experimental assays in human or yeast cells.
(?)
Select: multiple criteria
Retrieve: structures
Use various tools to retrieve data on structure of mutant p53 proteins.
(?)
Search all datasets with SRS
SRS allow for multiple user-defined queries and data retrieval in table or html formats.
SRS integration provided by
Paolo Romano, IST, Genova, Italy.
Polymorphisms
Display
polymorphic sites with links to specialized databases.
(?)
Mouse models
Display mouse models with engineered TP53.
(?)
Protein interactions
Visit
Human Protein Reference Database to view p53 protein-protein interactions and post-translational modifications on p53.
The search functionality has been created by Lambda-plus
and further developed at IARC.
