IARC TP53 DATABASE - Tumor spectrum option
Online Analysis Of Somatic And Germline Mutations
Tumor Spectrum

With this option you can retrieve the type of tumors (tumor site) that are associated with specific types of mutations. Select a mutation event to get a histogram showing (1) for somatic mutations, the proportion of the selected mutations by tumor sites (percent of the total number of mutations present in the database for each tumor site), (2) for germline mutations, the type of tumors that have been reported in individuals who are confirmed carriers of the selected mutation(s) (percent of the total number of tumors reported in these individuals). The selected data can be downloaded from the chart window.

Select a mutation:
Nucleotide number = (see NC_000017-9 reference sequence)   Mutant base :  (e.g. T)

Codon number = (1 to 393)  or  Codon number > and/or  <
WT AA:  (e.g. his or STOP) WT codon:  (e.g. CAG)
Mutant AA:  (e.g. his or STOP) Mutant codon:  (e.g. CAG)
ExonIntron:
Struc./Funct. Motif:
Type:
Description:
Effect:


In the scrollbar menus, multiple selection is possible by using the Ctrl key.

Sequences and tools