Selected references: Analyses of the IARC TP53 database

Petitjean A, Mathe E, Kato S, Ishioka C, Tavtigian SV, Hainaut P, Olivier M.
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database.
Hum Mutat. 2007 Jun;28(6):622-9. Pubmed

Petitjean A, Achatz MI, Borresen-Dale AL, Hainaut P, Olivier M.
TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes.
Oncogene. 2007 Apr 2;26(15):2157-65. Pubmed

Kawaguchi T, Kato S, Otsuka K, Watanabe G, Kumabe T, Tominaga T, Yoshimoto T, Ishioka C.
The relationship among p53 oligomer formation, structure and transcriptional activity using a comprehensive missense mutation library.
Oncogene. 2005 Oct 20;24(46):6976-81. Pubmed

Olivier M, Hussain SP, Caron de Fromentel C, Hainaut P, Harris CC.
TP53 mutation spectra and load: a tool for generating hypotheses on the etiology of cancer.
IARC Sci Publ. 2004 (157):247-70. PubMed

Olivier M, Goldgar DE, Sodha N, Ohgaki H, Kleihues P, Hainaut P, Eeles RA.
Li-Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype.
Cancer Res. 2003 Oct 15;63(20):6643-50. PubMed

Kato S, Han SY, Liu W, Otsuka K, Shibata H, Kanamaru R, Ishioka C.
Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis.
Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8424-9. PubMed

Pfeifer GP, Denissenko MF, Olivier M, Tretyakova N, Hecht SS,Hainaut P.
Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers.
Oncogene 2002 Oct 21;21(48):7435-51. PubMed

Martin AC, Facchiano AM, Cuff AL, Hernandez-Boussard T, Olivier M,Hainaut P, Thornton JM.
Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein.
Hum Mutat 2002 Feb;19(2):149-64. PubMed

Hainaut P, Olivier M, Pfeifer GP.
TP53 mutation spectrum in lung cancers and mutagenic signature of components of tobacco smoke: lessons from the IARC TP53 mutation database.
Mutagenesis 2001 Nov;16(6):551-3; author reply 555-6 PubMed

Olivier M, Hainaut P.
TP53 mutation patterns in breast cancers: searching for clues of environmental carcinogenesis.
Semin Cancer Biol 2001 Oct;11(5):353-360. PubMed

Hainaut P., Hollstein M.
p53 and human cancer: the first ten thousand mutations.
Adv Cancer Res. 2000 77:81-137 PubMed

Hernandez-Boussard T, Montesano R, Hainaut P.
Sources of bias in the detection and reporting of p53 mutations in human cancer: analysis of the IARC p53 mutation database.
Genet Anal. 1999 Feb;14(5-6):229-33 PubMed

Hernandez-Boussard TM, Hainaut P.
A specific spectrum of p53 mutations in lung cancer from smokers: review of mutations compiled in the IARC p53 database.
Environ Health Perspect. 1998 Jul;106(7):385-91. Erratum in: Environ Health Perspect 1998 Sep;106(9):A 421 PubMed