This fourth p53 mutant workshop was held in Akko (also named Acre), Israel. It covered topics ranging from the origin of mutations to their biological and clinical impacts and therapeutic use in human cancers. A special emphasis was put on animal models and on preclinical, in vivo data.

As for the 2nd and 3rd workshops, the annual meetings of two research consortiums working on p53 and funded by the European Community were held in conjunction with this international workshop. The Active p53 consortium meeting took place on 26 March 2009 and the MUTp53 consortium meeting on 30 March 2009. The consortium meetings were on invitation only.

A review article, "Recent advances in p53 research: an interdisciplinary perspective", that summarizes findings presented at the 3rd Workshop is freely available on Cancer Gene Therapy website.

Reports and abstracts from previous workshops are available at http://www-p53.iarc.fr/Events.html.

Giovanni BLANDINO, Rome, Italy
Michelangelo CORDENONSI, Padua, Italy
Giannino DEL SAL, Trieste, Italy
Wolfgang DEPPERT, Hamburg, Germany
Assaf FRIEDLER, Jerusalem, Israel
Pierre HAINAUT, Lyon, France
Curtis C. HARRIS, Bethesda, USA
Ygal HAUPT, Jerusalem, Israel
Monica HOLLSTEIN, Leeds, UK
Andreas JOERGER, Cambridge, UK
Gigi LOZANO, Houston, USA
Jeffrey MYERS, Houston, USA

Magali OLIVIER, Lyon, France
Moshe OREN, Rehovot, Israel
Carol PRIVES, New York, USA
Mike RESNICK, Research Triangle Park, USA
Varda ROTTER, Rehovot, Israel
Galina SELIVANOVA, Stockholm, Sweden
Zippora SHAKKED, Rehovot, Israel
Silvia SODDU, Rome, Italy
Hein TE RIELE, Amsterdam, The Netherlands
Genrich TOLSTONOG, Hamburg, Germany
Klas WIMAN, Stockholm, Sweden

Organizing Committee:

Pierre Hainaut*, International Agency for Research on Cancer, France,
Magali Olivier*, International Agency for Research on Cancer, France,
Varda Rotter, Weizmann Institute of Science, Israel
Moshe Oren, Weizmann Institute of Science, Israel
Klas Wiman, Karolinska Institute, Sweden
Giovanni Blandino, Regina Elena National Cancer Institute, Italy

Administrative assistants:

Vivienne Laufer, Weizmann Institute of Science
Administrative Assistant to Prof. Varda Rotter
Department of Molecular Cell Biology
Weizmann Institute of Science
Rehovot 76100, ISRAEL
Tel: +972-8-934-4072
Fax: +972-8-934-4125
Email: vivienne.laufer@weizmann.ac.il

Michelle Wrisez, International Agency for Research on Cancer
Group of Molecular Carcinogenesis and Biomarkers
International Agency for Research on Cancer
150 Cours Albert Thomas
F-69372 Lyon CEDEX 08
France
Tel: 33 472 738 462
Fax: 33 472 738 322
Email: .

Land arrangements organized by:
Bob Kazmer
Target Conferences Ltd., PO Box 29041, Tel Aviv 61290, Israel
Tel: +972 3 5175150, Fax: +972 3 5175155, e-mail: p53@targetconf.com