IARC TP53 DATABASE - Cell-line search option

TP53 Gene Status In Cell-lines

With this option you can search for cell-lines that have been screened for TP53 gene mutation. Data were extracted from published papers and from the Sanger Cancer Cell Line Project (identified as Ref_ID 2056 in the result table). Please note that several cell_lines linked to Ref_ID 2056 (COSMIC database) were wrongly annotated as WT in previous releases. This mistake has been corrected in the current version.

       

Cell-line name:
*search tips
TP53 status:
ATCC_ID:


COSMIC_ID:
Tumor origin:
Topography:
Morphology:

Mutation detection method

Start_material:
Exons analyzed:


Mutation description*

ExonIntron:
Type:
Description:
Effect:
Struct-Function Motif:


Nucleotide number =   (see NC_000017-9 reference sequence)   Mutant base :  (e.g. T)

Codon number   =     (1 to 393)   or   >  and/or < 
WT AA:  (e.g. his or STOP)  AA letter code WT Codon:  (e.g. CAG)
Mutant AA:  (e.g. his or STOP)  Genetic code Mutant codon:  (e.g. CAG)

* selection of a mutation type will return a list of cell-lines carrying this mutation, but only the selected mutation will be displayed.
To view the complete mutation status of a specific cell-line (some cell-lines may contain several mutations), make a new query with the cell-line name.



Patient from whom the cell-line has been isolated


Age > and/or < Sex
Germline mutation
Country
Population
Infectious agent
Tobacco:
Alcohol:
Exposure: